BioinformaticsBioinformaticsPeer-reviewed journal article
AlphaPulldown2 - A General Pipeline for High-Throughput Structural Modeling
Dmitry S. MolodenskiyiD, Valentin J. MaureriD, Dingquan YuiD, Grzegorz ChojnowskiiD, Stefan BienertiD, Gerardo TaurielloiD, Konstantin GilepiD, Torsten F. SchwedeiD, Jan KosińskiiD
Abstract
AlphaPulldown2 streamlines protein structural modeling by automating workflows, improving code adaptability, and optimizing data management for large-scale applications. It introduces an automated Snakemake pipeline, compressed data storage, support for additional modeling backends like UniFold and AlphaLink2, and a range of other improvements. These upgrades make AlphaPulldown2 a versatile platform for predicting both binary interactions and complex multi-unit assemblies. AvailabilityAlphaPulldown2 is freely available at https://github.com/KosinskiLab/AlphaPulldown.
- Citations
- 15
- FWCI
- 4.48
- Field percentile
- top 4%
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