Sign in
Molecular BiologyScientific Reports
Peer-reviewed journal article

AePUb promoter length modulates gene expression in Aedes aegypti

Michelle A. E. AndersoniD, Philip T. LeftwichiD, Ray Wilson, Leonela Carabajal PaladinoiD, Sanjay BasuiD, Sara RooneyiD, Zach N. AdelmaniD, Luke AlpheyiD

Abstract

Molecular tools for modulating transgene expression in Aedes aegypti are few. Here we demonstrate that adjustments to the AePUb promoter length can alter expression levels of two reporter proteins in Ae. aegypti cell culture and in mosquitoes. This provides a simple means for increasing or decreasing expression of a gene of interest and easy translation from cells to whole insects.

02 /Specification & Classification

Click any tag to browse matching papers
Citations
3
FWCI
0.77
Field percentile
top 28%

Reproducibility ledger

Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.

Sign in to file a reproducibility report.

Similarity Map
SelectedSame fieldCross-field
THISZhao '21Bui '22Ahmed '20Santos '25Leftwich '23Hout '23
57% semantic matchNeuroscience
Zhilei Zhao, David Tian, Carolyn S. McBride·Cell Reports Methods·Jun 30, 2021· 53 citations