Astrocyte mitochondria produce nitric oxide from nitrite to modulate cerebral blood flow during brain hypoxia
Isabel N. Christie, Shefeeq M. Theparambil, Maxim Doronin, Patrick Steven Hosford, Alexey Brazhe, Adrian J. Hobbs, Alexey V. Semyanov, Andrey Y. Abramov, Plamena R. Angelova, Alexander V. Gourine
The paper shows astrocytes produce nitric oxide from nitrite via mitochondrial sulfite oxidase during hypoxia, modulating cerebral blood flow.
bioRxiv · Mar 13, 2022 · PreprintNeuroscience