Advanced MRI Techniques and Applications

Multi-cohort, multi-sequence harmonisation for cerebrovascular brain age

This paper improves cerebrovascular brain age predictions by harmonizing arterial spin labeling (ASL) features across multiple cohorts using various methods, showing that ASL-specific harmonization enhances model performance.

Arterial spin labelling perfusion MRI analysis for the Human Connectome Project Lifespan Ageing and Development studies

The paper develops a processing pipeline for arterial spin labelling MRI data from the Human Connectome Project Lifespan and finds age-related differences in cerebral perfusion and transit times.

Normative trajectories of R1, R2* and magnetic susceptibility in basal ganglia on healthy ageing

This study establishes normative trajectories of R1, R2*, and magnetic susceptibility in the basal ganglia across healthy ageing using Gaussian Process Regression.

Characterising the association between posterior parietal metabolite levels and cortical macrostructure in a cohort spanning childhood to adulthood.

This study examines the relationship between posterior parietal metabolite levels and cortical macrostructural metrics in a developmental cohort, finding significant associations between metabolites and structural features like thickness and gyrification.

Velocity-selective arterial spin labelling bolus duration measurements: Implications for consensus recommendations

This paper measures bolus duration in VSASL MRI and shows that imaging after the trailing edge arrives can underestimate perfusion, suggesting adjustments to experimental design.

Fast and reliable quantitative measures of white matter development with magnetic resonance fingerprinting

This paper evaluates the reliability and validity of Magnetic Resonance Fingerprinting (MRF) for measuring white matter T1 values in children, finding improved reliability with longer scan duration but not B0 correction.

Ultra-low-field brain MRI morphometry: test-retest reliability and correspondence to high-field MRI

This study evaluates the reliability and correspondence of ultra-low-field MRI morphometry to high-field MRI, showing high reliability and correspondence across scan resolutions and contrasts.

Functional Magnetic Resonance Spectroscopy of Prolonged Motor Activation using Conventional and Spectral GLM Analyses

The paper compares conventional spectral fitting and direct linear modelling of fMRS data during a prolonged motor task, finding increased lactate but inconsistent glutamate changes.

Comparing the effect of multi gradient echo and multi band fMRI during a semantic task

This study compares multi gradient echo and multi band fMRI protocols during a semantic task, finding multi-band improves activation detection and decoding, while multi-echo enhances sensitivity in susceptibility-prone regions.

Visual stimulus-evoked blood velocity responses in individual human posterior cerebral arteries measured with dynamic phase-contrast functional MR angiography

This study introduces a new fMRA method to measure dynamic blood velocity responses in human posterior cerebral arteries during visual stimulation, showing a 10% increase in velocity and indicating neurovascular coupling.

The developing Human Connectome Project fetal functional MRI release: Methods and data structures

The paper describes the release of a large fetal fMRI dataset and presents methods for its preprocessing and analysis to study in utero brain connectivity.

Quantitative mapping of cerebrovascular reactivity amplitude and delay with breath-hold BOLD fMRI when end-tidal CO2 quality is low

This paper develops methods to estimate cerebrovascular reactivity (CVR) amplitude and delay in breath-hold fMRI when PETCO2 data quality is low, using rescaled RVT and deep learning-predicted PETCO2.

Ultra-low-field paediatric MRI in low- and middle-income countries: super-resolution using a multi-orientation U-Net

This paper develops a deep learning model to enhance ultra-low-field MRI scans for pediatric neurodevelopmental research, achieving better reconstruction of brain structures than existing methods.

A 3D-printed cradle for mouse preclinical MRI with an integrated water heating system

This paper describes a 3D-printed cradle for mouse MRI with an integrated water heating system to maintain body temperature during scans.

Ultra-high temporal resolution 4D angiography using arterial spin labeling with subspace reconstruction

This paper introduces a method to achieve ultra-high temporal resolution 4D angiography using arterial spin labeling with subspace reconstruction, improving spatiotemporal fidelity and temporal resolution.

Spanning spatial scales with functional imaging in the human brain; initial experiences at 10.5 Tesla

This paper presents initial results of 10.5 Tesla fMRI in humans, showing improved spatial resolution and functional contrast compared to 7 Tesla.

High-resolution awake mouse fMRI at 14 Tesla

This paper develops a high-resolution awake mouse fMRI platform to map sensory processing in association cortices, revealing anticipatory brain activity during vibrissa stimulation.

Macromolecule modelling for improved metabolite quantification using short echo time brain 1H-MRS at 3 T and 7 T: The PRaMM Model

The paper introduces a novel macromolecule quantification model (PRaMM) for improved metabolite quantification in brain 1H-MRS, showing better fit quality compared to existing methods.

Frequency-tagged fMRI: A platform for fine-grained spatiotemporal analysis of cortical function

This paper develops and validates a dual-frequency tagging fMRI protocol to enable fine-grained spatiotemporal analysis of cortical function, revealing detailed cortical topographies and temporal synchronization.

Macrovascular contributions to resting-state fMRI signals: A comparison between EPI and bSSFP at 9.4 Tesla

This study compares the macrovascular contribution of different fMRI sequences at 9.4 Tesla, finding that bSSFP shows lower macrovascular signal dependence than EPI sequences.

Multi-echo Acquisition and Thermal Denoising Advances Precision Functional Imaging

This paper introduces multi-echo acquisition and thermal denoising methods to improve precision functional MRI in adults, children, and newborns, showing increased signal-to-noise ratio and reliability.

Dynamic B0 field shimming for improving pseudo-continuous arterial spin labeling at 7 Tesla

This paper develops a dynamic B0 field shimming method for 7T PCASL to improve labeling efficiency and perfusion signal by correcting off-resonance in brain-feeding arteries.

Modelling inter-shot variability for robust temporal sub-sampling of dynamic, GABA-edited MR spectroscopy data

This paper develops a model to reduce unwanted variance in GABA-edited MRS data while preserving functional dynamics, showing improved SNR and reduced variability in GABA+ estimates.

UltimateSynth: MRI Physics for Pan-Contrast AI

UltimateSynth synthesizes realistic MRI images across diverse contrasts to train AI models that generalize across scanner types, sequences, and age groups, achieving robust tissue segmentation with low variability.

Assessing the feasibility of a new approach to measure the full spectrum of CSF dynamics within the human brain using MRI: insights from a simulation study

This study evaluates a new MRI method using simulations to measure full CSF dynamics in the brain, showing it can accurately separate motion components despite model assumptions.

Mapping glymphatic solute transportation through the perivascular space of hippocampal arterioles with 14 Tesla MRI

This study uses high-resolution MRI to map glymphatic transport in deep brain regions by directly infusing Gd into the lateral ventricle and analyzing PVS signal enhancements.

ProFit-1D for quantifying J-difference edited data at 3T

ProFit-1D was adapted to fit J-difference edited spectra at 3T and showed higher accuracy and precision than existing software for estimating metabolite concentrations.

Direct MRI of Collagen

This paper demonstrates direct in vivo collagen imaging using MRI with microsecond echo times, enabling collagen-specific depiction through echo subtraction.

Absolute quantification of cerebral metabolites using 2D 1H-MRSI with quantitative MRI-based water reference

This paper develops a fast method to quantify cerebral metabolites using 2D 1H-MRSI with a quantitative MRI-based water reference, showing improved accuracy over traditional methods.

Macrovascular blood flow and microvascular cerebrovascular reactivity are regionally coupled in adolescence

This study examines macrovascular and microvascular coupling in adolescents using 4D flow MRI and BOLD reactivity, finding age-related changes in cerebrovascular responses.