Ophthalmology and Visual Impairment Studies

Genetic network regulating visual acuity makes limited contribution to visually guided eye emmetropization

The paper investigates the role of the retinal genetic network regulating visual acuity in visually guided eye emmetropization and finds it has a limited contribution.

Genome-wide analysis of retinal transcriptome reveals common genetic network underlying perception of contrast and optical defocus detection

The paper uses genome-wide RNA-seq to analyze retinal genetic networks involved in contrast perception and optical defocus detection, revealing their role in myopia development.

Retinal glial cells under hypoxia possibly function in mammalian myopia by responding to mechanical stimuli, affecting hormone metabolism and peptide secretion

The paper investigates the role of retinal glial cells under hypoxia in mammalian myopia by analyzing gene expression and pathways related to mechanical stimuli and hormone metabolism.

The Effect of Refractive Blur in the Vividness of Mental Imagery

The study investigates how refractive blur affects the vividness of mental imagery, finding that it significantly reduces vividness in most participants.

Identification of ADAMTS19 as a novel retinal factor involved in ocular growth regulation

The paper identifies ADAMTS19 as a retinal factor that compensates for impaired ocular growth in PRSS56 and MFRP mutant mice, highlighting its role in axial length regulation.

Analysis of genetic networks regulating refractive eye development in collaborative cross progenitor strain mice reveals new genes and pathways underlying human myopia

The paper identifies genes and pathways regulating refractive eye development in mice and links them to human myopia, revealing distinct genetic networks for baseline development and environmental susceptibility.

Human Foveal Cone Photoreceptor Topography and its Dependence on Eye Length

The paper measures foveal cone density in relation to axial length in living eyes and finds that myopes have higher angular sampling density despite retinal stretching.

Inverse occlusion, a binocularly motivated treatment for amblyopia

This study shows that short-term inverse occlusion improves binocular balance, visual acuity, and stereo acuity in adults and older children with amblyopia.

Non-uniform genetic effect sizes of variants associated with refractive error suggests gene-gene or gene-environment interactions are pervasive

The paper shows that most genetic variants associated with refractive error exhibit non-uniform effect sizes, suggesting widespread gene-gene or gene-environment interactions.