Topic · Health, Toxicology and Mutagenesis · Environmental Science

Effects and risks of endocrine disrupting chemicals

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

2 papers

Exposure to p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) Perturbs Cell State and Stem Cell Markers and Induces an Epidermal Phenotype in Human Breast Cells

Jenna L Miller, Anagha Tapaswi, Jesse W. Wotring, Katelyn M. Polemi, Penghui Yang, Xiang Zhou, Laurie Kathleen Svoboda, Jonathan Z. Sexton, Justin A. Colacino

This study shows that DDE exposure alters cell state and stem cell markers in breast cells, inducing an epidermal phenotype and upregulating keratinization pathways.

bioRxiv · Oct 20, 2026 · PreprintPharmacology & Toxicology

Dose-additive and dose-dependent fetal testis toxicity of a nine-phthalate mixture in the rat

Joceline Helmbreck, Ziqi Zhao, Poonam Mehta, Patrick G. Schupp, Aditi Marehalli, Jason A. Scott, Matthew J. Woodcock, Andre Gomes, Cindy Su, Matthew Manwaring, Claire Gould, Thaís Del Rosario Hernández, Petra den Hollander, Susan J. Hall, Adina Badea, , Daniel J. Spade

This study shows that a nine-phthalate mixture causes dose-additive fetal testis toxicity in rats, including MNGs and reduced testosterone, with the lowest effective dose for MNGs.

bioRxiv · Oct 17, 2026 · PreprintPharmacology & Toxicology