Neonatal and Maternal Infections

GBS-SBG - GBS Serotyping by Genome Sequencing

This paper introduces GBS-SBG, a serotyping tool for Group B Streptococcus using genome sequencing, achieving high concordance with PCR-based methods on both short-read and assembly data.

Genetic study of late-onset neonatal sepsis reveals significant differences by sex

This study identifies genetic risk factors for late-onset neonatal sepsis, finding sex-specific associations and significant SNP-sex interactions.

Genomic insights on DNase production in Streptococcus agalactiae ST17 and ST19 strains

The paper compares genomic differences between DNase-producing and non-producing Streptococcus agalactiae strains to identify genetic factors associated with DNase activity and virulence.

Global gene expression analysis of Streptococcus agalactiae at exponential growth phase

The paper performs RNA-sequencing to analyze global gene expression of S. agalactiae NEM316 during exponential growth, identifying translation-related genes and highlighting gaps in understanding DNase release mechanisms.

Pan-GWAS of Streptococcus agalactiae highlights lineage-specific genes associated with virulence and niche adaptation

This study performs a pan-GWAS of Streptococcus agalactiae strains to identify lineage-specific genes linked to virulence and niche adaptation across different host environments.

Temporal population structure of invasive Group B Streptococcus during a period of rising disease incidence shows expansion of a CC17 clone

The paper uses whole genome sequencing to analyze invasive GBS isolates in the Netherlands and identifies the expansion of a CC17 sub-lineage, CC17-1A, as correlated with increased disease incidence.

Vital Signs Analysis Algorithm Detects Inflammatory Response in Premature Infants with Late Onset Sepsis and Necrotizing Enterocolitis

The paper evaluates the RALIS algorithm for early detection of late onset sepsis and necrotizing enterocolitis in premature infants using vital signs data.