ATP Synthase and ATPases Research

Oligomeric hypercomplex of the complete oxidative phosphorylation system in heart mitochondria.

This study uses cryo-electron tomography to reveal the supramolecular architecture of the oligomeric hypercomplex in rat heart mitochondria, showing direct proton transfer between respiratory chain supercomplexes and ATP synthases.

Asymmetry in catalysis by Thermotoga maritima membrane-bound pyrophosphatase demonstrated by a non-phosphorous allosteric inhibitor

The paper demonstrates asymmetry in the catalytic cycle of membrane-bound pyrophosphatases using a non-phosphorous allosteric inhibitor bound to Thermotoga maritima enzyme.