Organ and Tissue Transplantation Research

Endothelial cell MHC molecules are necessary and sufficient to reject 3D-printed human skin grafts in an advanced human immune system mouse

The study shows that endothelial cell MHC molecules are critical for rejecting 3D-printed human skin grafts in an immunocompetent humanized mouse model.

Preservation Strategies for Vascularized Composite Allotransplantation: An Updated Systematic Review of a Rapidly Expanding Field

This paper reviews recent advances in vascularized composite allotransplantation preservation strategies, highlighting machine perfusion and supercooling as promising methods to extend graft viability.

A Precisely Controlled Long-Acting Immunosuppression Platform Enables Prolonged Survival of Vascularized Composite Allografts

PRECISE, a long-acting immunosuppression platform, maintains therapeutic drug levels and prolongs graft survival in VCA models through precise control of tacrolimus and rapamycin release.

A phrenic-sparing cephalic reanastomosis model: Acute effects and implications

This study evaluates a phrenic-sparing cephalic reanastomosis model in pigs using fusogens, showing recovery of ventilation and brain functions after spinal cord fusion.

Pre-treatments of Ex vivo Vascularized Composite Allografts: A Scoping Review

This paper reviews pre-treatment methods for vascularized composite allografts to improve graft viability and reduce rejection, finding ex vivo perfusion shows promise in preserving muscle function.