Topic · Physical and Theoretical Chemistry · Chemistry
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
5 papers
This study evaluates a novel isothermal microcalorimetry-based sterility test, finding it more sensitive and faster than the traditional USP sterility test.
Journal of Pharmaceutical Innovation · Aug 24, 2026Peer-reviewedMicrobiology
Matthew J. McLeod, Robert Edward Thorne
The paper examines how small temperature variations in enzyme activation parameters affect Arrhenius/Eyring modeling, leading to apparent enthalpy-entropy compensation and misinterpretation of kinetic data.
Protein Science · Jul 24, 2026Peer-reviewedBiophysics
Kanishka Panda, Rohith Mittapally, Qianqian Chen, Akshay Manoj Bhaskaran, Pramod Reddy, Edgar Meyhöfer, Swathi Yadlapalli
This study measures metabolic heat output of individual Drosophila brains to examine effects of sex, genotype, age, and disease on brain metabolism.
Cell Reports Methods · Jun 15, 2026Peer-reviewedBioengineering
Ivan Babić, Nikolas Bryan, Claire Cunningham, Avery M. Sampson, Daniel T. Starczynowski, Elmar Nurmemmedov
The paper introduces a fluorescence-based method to quantify drug-target engagement in temperature series using split-RNase S complementation.
SLAS DISCOVERY · Nov 22, 2025Peer-reviewedBiochemistry
Amir I. Mina, Raymond A. LeClair, Katherine B. LeClair, David E. Cohen, Louise Lantier, Alexander S. Banks
CalR is a web-based tool for analyzing indirect calorimetry data, offering statistical analysis, visualization, and standardized output to improve reproducibility and efficiency in metabolic experiments.
Cell Metabolism · Jan 1, 2018Peer-reviewedBioinformatics