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This paper introduces FLAME, a high-throughput 3D ultrasound imaging technique that significantly improves resolution and speed for microvascular imaging in mouse organs.

The paper introduces a source-level noise covariance model for resting-state MEG/EEG data, improving source reconstruction reliability by avoiding artificial baseline distortions.

This paper develops a composite microfiber-hydrogel scaffold using melt-electrowriting to enhance muscle tissue engineering by improving mechanical strength, alignment, and myoblast differentiation.

This paper develops an ingestible capsule for non-invasive optogenetic stimulation in rodents, demonstrating its functionality and safety in vivo.

This paper develops a subcutaneous delivery platform for ultra-high-concentration protein therapeutics using a copolymer excipient, enabling reduced injection volumes and improved stability.

This study develops a method to quantify subtendon sliding in the Achilles tendon using ultrasound and electrical stimulation, finding differential displacement patterns based on stimulated muscle.

This paper develops an in vivo method to covalently link peptide drugs to native IgGs, demonstrating sustained weight loss and glucose management with GLP-1.

This study shows that reducing flight time during running lowers tibial-fibular strains, suggesting grounded running may reduce stress fracture risk.

This paper computationally designs soluble CCR8 analogues that retain native antibody binding, achieving a 62% success rate with preserved structural and functional properties.

Protpardelle-1c is a protein structure generative model that improves motif scaffolding and multi-chain complex generation, achieving higher scores and faster sampling than existing models.

This study examines how changes in collagen gel elasticity and fibril density affect cell adhesion, showing opposing effects when both parameters increase.

This study develops a biocompatible polymeric resin for dental adhesion, showing improved bond strength and biocompatibility through triacrylate-trithiol crosslinking.

This paper introduces a phantom and analysis code to assess fluorescence uniformity and distortion in surgical imaging systems, finding that flat-field correction improves image appearance but may reduce quantitative accuracy.

This study develops ECM-decorated biodegradable scaffolds as synthetic periosteal grafts, showing improved cell growth and angiogenic effects in vitro.

This study shows that norbornene homopolymerization limits cell spreading in thiol-ene hydrogels, and reducing norbornene density improves hydrogel relaxation and cell morphology.

This paper designs chimeric collagen-like proteins to create nanocomplexes for targeted doxorubicin delivery, showing enhanced tumor accumulation and reduced toxicity.

This paper introduces a label-free endoscopic platform combining Raman spectroscopy and OCT to track morphomolecular changes in real-time during carcinogenesis, enabling early cancer detection.

This study shows that a synthetic hydrogel enables crypt formation in intestinal organoids without exogenous laminin, revealing insights into mechanical and matricellular signaling.

This paper edits the ADA2 p.R169Q mutation in human hematopoietic stem cells using CRISPR-Cas9 and HDR, showing improved efficiency with NHEJ inhibitors but increased chromosomal deletions.

This study shows that personal lubricants can deliver the Human Contraception Antibody (HCA) effectively, with silicone-based formulations showing higher delivery efficiency.