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The paper constructs a sorghum pangenome from ex-PVP cultivars and a wild accession, identifying structural variants and selective sweeps linked to adaptation and trait improvement.

This study examines genetic differentiation in Culex tarsalis mosquitoes, showing environmental factors influence their genetic makeup and adaptation to climate change.

This study uses next-generation sequencing to analyze HBV and HDV genotypes and mutations in Peruvian samples, identifying genotype F for HBV and genotype 3 for HDV with associated clinical mutations.

The paper annotates mitochondrial genomes of Neotropical raptors and designs metabarcoding primers for environmental DNA applications to aid conservation.

This paper evaluates how hyperparameters affect prediction stability and performance in genomic prediction for wheat breeding using Gradient Boosting Machines.

The paper investigates somatic mutation variation in walnut clones propagated through different methods, finding high mutation rates and genomic instability in somatic embryos.

The paper shows that disease-associated variants in alternative protein isoforms can cause structural mutations, emphasizing the need to consider tissue-specific expression and full-length transcripts in variant interpretation.

The paper optimizes the iMAP CRISPR platform to reduce recombination bias, profiles RNA modification factors across mouse tissues, and identifies context-specific functions with therapeutic implications.

The paper benchmarks 44 tools for plasmidome reconstruction from short-read assemblies in Klebsiella pneumoniae, finding PlaScope and MOB-suite as top performers.

The paper investigates the evolutionary origins of DNA methylation, finding it was likely acquired from bacterial donors to silence transposable and viral elements across eukaryotes.

The paper presents the first Arab Pangenome Reference using long-read and Hi-C data, revealing novel sequences and variants specific to Arab populations.

The paper develops RoboATAC, an automated ATAC-seq method, to study how TF dosage affects chromatin accessibility and gene expression, finding that DNA sequence predicts dosage sensitivity and nucleosome positioning patterns vary by TF.

The paper investigates the relationship between insertion sequences (IS) and metabolic capacity in four Klebsiella pneumoniae sub-lineages, finding higher IS loads correlate with reduced metabolic gene numbers and substrate utilisation.

The paper uses long-read sequencing to characterize structural variants in 1,019 samples from the 1000 Genomes Project, identifying 167,291 sequence-resolved SVs and highlighting their genomic and functional implications.

The paper develops a rapid, cost-effective nanopore sequencing protocol and bioinformatics dashboard for continental-scale genomic surveillance of Plasmodium falciparum malaria in sub-Saharan Africa.

This study evaluates three rRNA depletion kits for their performance in parasitic nematodes, finding Zymo-Seq most effective with minimal bias.

This study investigates ZIC2's role in neural development, showing it acts as a pioneer transcription factor during pluripotency exit and an enhancer activator during neural induction.

This study introduces szKendall, a dissimilarity measure for scHi-C data that accounts for structural zeros, improving cell clustering performance.

The paper introduces SpaceDecorr, a method to reduce false-positive correlations in spatial transcriptomics data by adjusting for spatial dependencies and technical artifacts.

The paper evaluates the Illumina Complete Long Read (ICLR) assay for metagenomic assembly, finding it produces higher contiguity and completeness compared to short-read and nanopore long-read methods.