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This study shows LSD1 represses mesenchymal genes in epithelial cells, maintaining epithelial identity, and challenges the therapeutic use of LSD1 inhibition for EMT control.

The paper evaluates Dorado and Barbell preprocessing tools for metagenomic reads, finding Barbell reduces barcode-like sequences more effectively while retaining most reads.

This study shows that satellite cell glucocorticoid receptor (GR) maintains quiescence but does not mediate therapeutic GC effects on muscle repair, highlighting the importance of treatment timing and context.

This study compares a seed amplification assay for alpha-synuclein aggregates with immunohistochemistry in intestinal biopsies of Parkinson's disease and multiple system atrophy patients, finding the assay detects aggregates more frequently and with higher specificity.

This study identifies FUL2 and STM3 as repressors of secondary growth in tomato stems, showing their role in limiting xylem accumulation during stem development.

The paper measures Raman spectra of microtubules and tubulin at various temperatures to investigate Fano resonance asymmetry in molecular bond vibrations.

The paper analyzes centromere evolution in oaks, showing lineage-specific expansion of QuCEN146 satellite drives turnover, while LTR-rich centromeres show low polymorphism due to suppressed recombination.

The paper identifies the CCAAT-binding complex (CBC) as a key regulator that overrides genetic sterility in Candida albicans by integrating environmental stress signals to enable mating.

The paper develops a biophysical model of the SCN to explain circadian rhythm splitting under chronic light and shows how E/I balance and chloride cotransporter dynamics drive this behavior.

The paper explores whether quantum entanglement, measured via von Neumann Entropy, influences TP53 mutation patterns, finding elevated entropy at known mutational hotspots but cautioning about limited validation.

This study identifies middle ear dysfunction as the primary cause of residual hearing loss in chronically implanted guinea pigs, suggesting a conductive mechanism.

The paper identifies a druggable CSNK2A1-MeCP2 regulatory axis linking Okur-Chung neurodevelopmental syndrome with MECP2-related disorders through CRISPR screens and mouse models.

This paper introduces hybrid RY-mers to improve aDNA alignment sensitivity and efficiency, showing higher accuracy and reduced runtime compared to existing methods.

This study shows that cyanobacteria respond to yeast partners only when co-localized, not just through metabolite exchange.

This study identifies coordinated angiogenesis-EMT gene programs in OSCC using multi-omic analysis and validates candidate genes through external datasets and protein-level confirmation.

This study identifies surface proteins in Asgard archaea using visual surfaceomics, revealing a peptidophilic cell surface involved in peptide capture and symbiotic interactions.

The paper uses R-DeeP to show stress-induced compartment-specific RNA buffering of protein aggregation in yeast, with nuclear RNA retention protecting nuclear proteins from aggregation.

The paper distinguishes human and livestock-associated Salmonella Typhimurium isolates using genomic signatures and machine learning.

The paper shows isoform diversity is a distinct dimension of gene expression, complementary to gene-level abundance, and changes with age and tissue-specific processes.

The paper examines how personality and dominance affect core area use and territory-related signaling in Asian water buffalo.