Oksana Gonchar

This study shows LSD1 represses mesenchymal genes in epithelial cells, maintaining epithelial identity, and challenges the therapeutic use of LSD1 inhibition for EMT control.

This study identifies primary targets of individual class I HDAC complexes and shows that their rapid degradation leads to gene regulation with significant specificity and antagonistic effects.

This study identifies Cdk1-mediated phosphorylation of Sam68 at T33 and T317, showing it reduces RNA binding and alternative splicing activity, promoting cell proliferation and inhibiting apoptosis in HCT116 cells.