Johanna Franziska Seidler

The paper uses R-DeeP to show stress-induced compartment-specific RNA buffering of protein aggregation in yeast, with nuclear RNA retention protecting nuclear proteins from aggregation.

This study identifies Yra1 phosphorylation as a mechanism that inhibits bulk mRNA export during heat stress while promoting selective export of heat-induced transcripts in S. cerevisiae.

The paper profiles RNA-dependent proteins in two yeast species, identifies a conserved core and species-specific adaptations, and introduces R-DeeP as a tool for RNA-protein interaction analysis.

This study identifies Pin4 as a yeast RNA-binding protein that coordinates post-transcriptional and transcriptional responses to energy depletion by regulating mRNA binding and transcriptional shifts during glucose withdrawal.