Cancer BiologybioRxivPreprint
Regulation of DNA damage response by trimeric G-protein Signaling
A. A. Abd El-Hafeez, N. Sun, A. Chakraborty…·P. Ghosh
This paper shows that GIV/Girdin modulates DNA damage response by suppressing HR and promoting NHEJ through BRCA1 sequestration and Akt pathway activation.
DOI 10.1101/2021.07.21.452842