Author

S. E. Kim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Organism:E. coli· 1

Frequent Co-Authors

D. F. Savage· 2 shared A. A. Ku· 1 shared A. Kimberlin· 1 shared A. L. Wolfe· 1 shared A. Seth· 1 shared A. Wozniak· 1 shared C. B. Lebrilla· 1 shared C. Jeans· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBioengineering

D. F. Savage

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Genome editing in the mouse brain with minimally immunogenic Cas9 RNPs

E. C. Stahl, J. K. Sabo, M. H. Kang, R. Allen, E. Applegate, S. E. Kim, Y. Kwon, A. Seth, N. Lemus, V. Salinas-Rios, K. Soczek, M. Trinidad, L. T. Vo, C. Jeans, A. Wozniak, , J. A. Doudna

This study demonstrates that minimally immunogenic Cas9 RNPs delivered via convection enhanced delivery can edit mouse striatal neurons with reduced immune responses compared to AAV-delivered Cas9.

bioRxiv · Apr 13, 2023Bioengineering

Two opposing effects of monovalent cations on the stability of i-motif structure

S. E. Kim, S.-C. Hong

The paper investigates how different monovalent cations affect i-motif stability, finding that they destabilize the structure despite their usual role in DNA folding.

bioRxiv · Sep 30, 2022Biophysics

Engineering improved Cas13 effectors for targeted post-transcriptional regulation of gene expression

E. J. Charles, S. E. Kim, G. J. Knott, D. Smock, J. Doudna, D. F. Savage

This paper engineers improved Cas13 effectors for targeted post-transcriptional regulation, showing efficient translational repression in bacteria and exon skipping in human cells.

bioRxiv · May 26, 2021 · PreprintBioengineering

UDP-glucose pyrophosphorylase 2, a regulator of glycosylation and glycogen, is essential for pancreatic cancer growth

A. L. Wolfe, Q. Zhou, E. Toska, J. Galeas, A. A. Ku, R. P. Koche, S. Bandyopadhyay, M. Scaltriti, C. B. Lebrilla, F. McCormick, S. E. Kim

This study identifies UGP2 as essential for pancreatic cancer growth by regulating glycogen and N-glycosylation, with potential therapeutic implications.

bioRxiv · Oct 13, 2020 · PreprintCancer Biology