Author

A. Barthelemy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Bongiovanni· 1 shared A. Plesa· 1 shared A. Sacchi· 1 shared B. L. Eldridge-Thomas· 1 shared C. Berthon· 1 shared C. PREUDHOMME· 1 shared C. Roubinet· 1 shared C. ROUMIER· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCancer Biology

A. Bongiovanni

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The transmembrane protein Syndecan regulates stem cell nuclear properties and cell maintenance.

B. L. Eldridge-Thomas, J. G. Bohere, C. Roubinet, A. Barthelemy, T. J. Samuels, F. Karam Teixeira, G. Kolahgar

This study identifies Syndecan's role in regulating nuclear properties and stem cell maintenance in Drosophila midgut and brain tissues.

bioRxiv · Feb 15, 2024 · PreprintCell Biology

Bromodomain proteins as new drug target for an inborn lysosomal defect

M. Parente, A. Barthelemy, C. Tonini, S. Caputo, A. Sacchi, S. Leone, M. Segatto, F. W. Pfrieger, V. Pallottini

This study investigates bromodomain proteins as a therapeutic target for Niemann-Pick type C disease, showing that JQ1 improves NPC1 levels and reduces cholesterol accumulation in patient-derived fibroblasts.

bioRxiv · Dec 19, 2023Cell Biology

Tetraspanin CD81 promotes leukemia stem cell function and represents a new therapeutic vulnerability in acute myeloid leukemia

F. Gonzales, P. Peyrouze, T. Boyer, S. Guihard, F. Sevrin, D. LAURENT, A. Plesa, A. Barthelemy, A. Bongiovanni, N. Pottier, C. PREUDHOMME, N. DUPLOYEZ, C. Berthon, C. ROUMIER, M. CHEOK

This study identifies CD81 as a marker of aggressive AML and shows anti-CD81 therapy improves survival in AML models.

bioRxiv · Sep 20, 2023 · PreprintCancer Biology