Author

C. Preudhomme

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

C. ROUMIER· 2 shared H. Dombret· 2 shared M. CHEOK· 2 shared A. Barthelemy· 1 shared A. Bongiovanni· 1 shared A. G. X. Zeng· 1 shared A. K. Kheirallah· 1 shared A. Krzywon· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCancer Biology

C. ROUMIER

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3 papers

Recent·Most cited

Tetraspanin CD81 promotes leukemia stem cell function and represents a new therapeutic vulnerability in acute myeloid leukemia

F. Gonzales, P. Peyrouze, T. Boyer, S. Guihard, F. Sevrin, D. LAURENT, A. Plesa, A. Barthelemy, A. Bongiovanni, N. Pottier, C. PREUDHOMME, N. DUPLOYEZ, C. Berthon, C. ROUMIER, M. CHEOK

This study identifies CD81 as a marker of aggressive AML and shows anti-CD81 therapy improves survival in AML models.

bioRxiv · Sep 20, 2023 · PreprintCancer Biology

A cellular hierarchy framework for understanding heterogeneity and predicting drug response in AML

A. G. X. Zeng, S. Bansal, L. Jin, A. Mitchell, W. C. Chen, H. A. Abbas, M. Chan-Seng-Yue, V. Voisin, P. van Galen, A. Tierens, M. Cheok, C. Preudhomme, H. Dombret, N. Daver, P. A. Futreal, , J. E. Dick

This study identifies a cellular hierarchy framework in AML that links disease heterogeneity with drug response and develops a 7-gene biomarker predictive of drug sensitivity.

bioRxiv · Jan 25, 2022Cancer Biology

A transcriptomic continuum of differentiation arrest identifies myeloid interface acute leukemias with poor prognosis

J. Bond, A. Krzywon, L. Lhermitte, C. Roumier, A. Roggy, M. Belhocine, A. K. Kheirallah, P. Villarese, G. Hypolite, F. Garnache-Ottou, S. Castaigne, N. Boissel, V. Asnafi, C. Preudhomme, H. Dombret, , E. Macintyre

The paper identifies a transcriptomic continuum of differentiation arrest in acute leukemias, finding that myeloid/T-lymphoid interface leukemias (IALs) correlate with poor prognosis in AML.

bioRxiv · Dec 10, 2019Cancer Biology