Tetraspanin CD81 promotes leukemia stem cell function and represents a new therapeutic vulnerability in acute myeloid leukemia
F. Gonzales, P. Peyrouze, T. Boyer, S. Guihard, F. Sevrin, D. LAURENT, A. Plesa, A. Barthelemy, A. Bongiovanni, N. Pottier, C. PREUDHOMME, N. DUPLOYEZ, C. Berthon, C. ROUMIER, M. CHEOK
This study identifies CD81 as a marker of aggressive AML and shows anti-CD81 therapy improves survival in AML models.
bioRxiv · Sep 20, 2023 · PreprintCancer Biology