Insights into Molecular Diversity within the FET Family: Unraveling Phase Separation of the N-Terminal Low Complexity Domain from RNA-Binding Protein EWS
C. N. Johnson, K. A. Sojitra, E. J. Sohn, A. K. Moreno-Romero, A. Baudin, X. Xu, J. Mittal, D. S. Libich
This study investigates the phase separation mechanism of the EWSLCD domain using biophysical methods, revealing tyrosine residues as key drivers of condensate formation.
bioRxiv · Oct 27, 2023 · PreprintBiophysics