Author

E. Y. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. Chen· 2 shared K. Baxi· 2 shared L. Wang· 2 shared M. S. Ignatius· 2 shared N. R. Hensch· 2 shared A. Bandyopadhyay· 1 shared A. Baudin· 1 shared A. E. Lipsitt· 1 shared

Activity by Year

2021-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

J. Chen

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Fanconi anemia-isogenic head and neck cancer cell line pairs - a basic and translational science resource

H. T. Nguyen, W. Tang, A. L. H. Webster, J. R. Whiteaker, C. M. Chandler, R. Errazquin, L. B. Sullivan, E. Jonlin, E. E. Hoskins, E. Y. Chen, M. Fritzke, A. G. Paulovich, S. I. Wells, K. Roohollahi, J. Dorsman, , R. J. Monnat

The paper develops isogenic head and neck cancer cell line pairs to study Fanconi anemia-associated cancers and their treatment.

bioRxiv · Sep 11, 2022Cancer Biology

Serum metabolomic analysis of men on a low-carbohydrate diet for biochemically recurrent prostate cancer reveal the potential role of ketogenesis to slow tumor growth: A secondary analysis of the CAPS2 diet trial

J.-T. A. Chi, P.-H. Lin, V. Tolstikov, L. Howard, E. Y. Chen, V. Bussberg, B. Greenwood, N. R. Narain, M. A. Kiebish, S. Freedland

This paper analyzes serum metabolomics from a low-carbohydrate diet trial in prostate cancer patients to identify metabolic changes associated with slower tumor growth.

bioRxiv · Dec 29, 2021Cancer Biology

The evolution of neurosensation drives the gain and loss of phenotypic plasticity

E. Y. Chen, D. K. Adams

The paper traces the evolution of phenotypic plasticity in echinoids, showing its origin in regular urchins and linking it to neurosensory system development and loss.

bioRxiv · Nov 29, 2021 · PreprintEvolutionary Biology

Defining function of wild-type and patient specific TP53 mutations in a zebrafish model of embryonal rhabdomyosarcoma

J. Chen, K. Baxi, A. E. Lipsitt, N. R. Hensch, L. Wang, A. Baudin, D. G. Robledo, A. Bandyopadhyay, A. Sugalski, A. K. Challa, A. R. Gilbert, G. E. Tomlinson, P. Houghton, E. Y. Chen, D. S. Libich, M. S. Ignatius

The paper defines the role of wild-type and patient-specific TP53 mutations in ERMS using zebrafish models, showing tp53 loss increases tumor initiation and identifying mutation-specific effects on tumor development.

bioRxiv · Apr 21, 2021Cancer Biology

SNAI2-mediated direct repression of BIM protects rhabdomyosarcoma from ionizing radiation

L. Wang, N. R. Hensch, K. Bondra, P. Sreenivas, X. R. Zhao, J. Chen, K. Baxi, R. M. Campos, B. Gryder, S. Pomella, R. Rota, E. Y. Chen, J. Khan, P. J. Houghton, M. S. Ignatius

This study identifies SNAI2 as a repressor of BIM, protecting rhabdomyosarcoma from ionizing radiation through a P53-independent mechanism.

bioRxiv · Jan 25, 2021Cancer Biology