Author

A. K. Challa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Bandyopadhyay· 1 shared A. Baudin· 1 shared A. E. Lipsitt· 1 shared A. N. Turner· 1 shared A. R. Gilbert· 1 shared A. Sugalski· 1 shared B. Eagleson· 1 shared C. J. Essenburg· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Bandyopadhyay

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Author profile →

3 papers

Recent·Most cited

Defining function of wild-type and patient specific TP53 mutations in a zebrafish model of embryonal rhabdomyosarcoma

J. Chen, K. Baxi, A. E. Lipsitt, N. R. Hensch, L. Wang, A. Baudin, D. G. Robledo, A. Bandyopadhyay, A. Sugalski, A. K. Challa, A. R. Gilbert, G. E. Tomlinson, P. Houghton, E. Y. Chen, D. S. Libich, M. S. Ignatius

The paper defines the role of wild-type and patient-specific TP53 mutations in ERMS using zebrafish models, showing tp53 loss increases tumor initiation and identifying mutation-specific effects on tumor development.

bioRxiv · Apr 21, 2021Cancer Biology

Physiological and Metabolic Features of Mice with CRISPR/Cas9-Mediated Loss-of-Function in Growth Hormone-Releasing Hormone

F. Zhang, S. Y. Liou, A. K. Challa, M. P. Fitch, M. Icyuz

This study shows that CRISPR/Cas9-generated GHRH-/- mice have reduced body weight, improved insulin sensitivity, and altered metabolism, consistent with previous findings on growth hormone deficiency.

bioRxiv · Feb 7, 2020Physiology

NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer

P. S. Dischinger, E. A. Tovar, C. J. Essenburg, Z. B. Madaj, E. E. Gardner, M. Callaghan, A. N. Turner, A. K. Challa, T. Kempston, B. Eagleson, R. A. Kesterson, R. T. Bronson, M. J. Bowman, C. R. Graveel, M. R. Steensma

This study shows NF1 deficiency in breast cancer correlates with estrogen receptor signaling and poor survival, using rat models and human genomic data.

bioRxiv · Feb 27, 2018Cancer Biology