Author

A. Bolomsky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Malyutina· 1 shared A. Mueller· 1 shared A. O. Parsons· 1 shared B. Haupl· 1 shared C. A. Heckman· 1 shared C. J. Thomas· 1 shared C. K. Van Winkle· 1 shared C. Klumpp-Thomas· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Malyutina

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2 papers

Recent·Most cited

Multi-omics data integration reveals molecular mechanisms of carfilzomib resistance in multiple myeloma

A. Malyutina, P. Sergeev, J. Huber, J. J. Miettinen, A. Bolomsky, J. Bao, A. O. Parsons, A. Mueller, N. Marella, M. van Duin, H. Ludwig, J. Tang, C. A. Heckman

This study identifies molecular mechanisms of carfilzomib resistance in multiple myeloma using multi-omics data from cell lines and patient samples, revealing potential drug combinations to overcome resistance.

bioRxiv · May 26, 2024 · PreprintCancer Biology

Oncogenic RAS commandeers amino acid sensing machinery to aberrantly activate mTORC1 in multiple myeloma

Y. Yang, T. Oellerich, P. Chen, A. Bolomsky, M. Ceribelli, B. Haupl, G. W. Wright, J. D. Phelan, D. W. Huang, J. W. Lord, C. K. Van Winkle, X. Yu, J. Wisnieski, J. Q. Wang, F. A. Tosto, , R. M. Young

This study identifies how oncogenic RAS activates mTORC1 in multiple myeloma by co-opting amino acid sensing pathways through a novel signaling complex.

bioRxiv · Nov 28, 2021Cancer Biology