Author

A. Bonfim-Melo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

A. S. Yap· 1 shared C. N. Duong· 1 shared D. Currin-Ross· 1 shared D. Vestweber· 1 shared E. Gordon· 1 shared I. Noordstra· 1 shared J. K. Pagan· 1 shared J. M. Kalappurakkal· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCell Biology

A. S. Yap

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A high-resolution, nanopore-based artificial intelligence assay for DNA replication stress in human cancer cells

M. J. K. Jones, S. K. Rai, P. L. Pfuderer, A. Bonfim-Melo, J. K. Pagan, P. R. Clarke, S. E. McClelland, M. A. Boemo

This paper introduces an AI-powered nanopore sequencing method to measure DNA replication stress in cancer cells, showing it can distinguish fork slowing from stalling and detect therapy-specific replication stress signatures.

bioRxiv · Sep 22, 2022Cancer Biology

An E-cadherin-actin clutch translates the mechanical force of cortical flow for cell-cell contact to inhibit epithelial cell locomotion

I. Noordstra, M. Diez Hermoso, L. Schimmel, A. Bonfim-Melo, D. Currin-Ross, C. N. Duong, J. M. Kalappurakkal, R. G. Morris, D. Vestweber, S. Mayor, E. Gordon, P. Roca-Cusachs, A. S. Yap

The paper explains how E-cadherin-actin interactions mediate mechanical signals from cortical flows to inhibit epithelial cell migration based on contact orientation.

bioRxiv · Jul 28, 2021Cell Biology