Yersinia pseudotuberculosis YopE prevents uptake by M cells and instigates M cell extrusion in human ileal enteroid-derived monolayers.
A. C. Fasciano, G. S. Dasanayake, M. K. Estes, N. C. Zachos, D. T. Breault, R. R. Isberg, S. Tan, J. Mecsas
This study uses human ileal enteroid-derived monolayers to show that Yersinia pseudotuberculosis YopE prevents uptake by M cells and causes their extrusion, facilitating bacterial transcytosis.
bioRxiv · Aug 23, 2021Microbiology