Author

J. Mecsas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

R. R. Isberg· 2 shared A. C. Fasciano· 1 shared B. B. Aldridge· 1 shared B. Peters· 1 shared D. B. Sykes· 1 shared D. K. Hunt· 1 shared D. T. Breault· 1 shared D. T. Hung· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

R. R. Isberg

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Massively parallel combination screen reveals small molecule sensitization of antibiotic-resistant Gram-negative ESKAPE pathogens

M. W. Tse, M. Zhu, B. Peters, E. Hamami, J. Chen, K. P. Davis, S. Nitz, J. Weller, T. Warrier, D. K. Hunt, Y. Morales, T. Kawate, J. L. Gaulin, J. H. Come, J. Hernandez-Bird, , P. C. Blainey

This study uses high-throughput screening to identify small molecules that enhance antibiotic efficacy against multidrug-resistant Gram-negative bacteria.

bioRxiv · Mar 26, 2024 · PreprintMicrobiology

Yersinia pseudotuberculosis YopE prevents uptake by M cells and instigates M cell extrusion in human ileal enteroid-derived monolayers.

A. C. Fasciano, G. S. Dasanayake, M. K. Estes, N. C. Zachos, D. T. Breault, R. R. Isberg, S. Tan, J. Mecsas

This study uses human ileal enteroid-derived monolayers to show that Yersinia pseudotuberculosis YopE prevents uptake by M cells and causes their extrusion, facilitating bacterial transcytosis.

bioRxiv · Aug 23, 2021Microbiology

Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation

G. T. Nguyen, S. Xu, S. C. Bunnell, M. K. Mansour, D. B. Sykes, J. Mecsas

This study shows SKAP2 is essential for neutrophil ROS production in response to C-type lectin receptors and Candida infections, expanding its role beyond antibacterial immunity.

bioRxiv · Mar 2, 2021Immunology