Author

A. Chumbe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:protein structure prediction· 2 Organism:chicken / avian· 1 Research Focus:clustering· 1 Assay:cryo-EM· 1 Organism:human· 1

Frequent Co-Authors

J. Schinkel· 2 shared K. Sliepen· 2 shared A. B. Ward· 1 shared A. Torrents de la Pena· 1 shared A. Underwood· 1 shared G. C. Lander· 1 shared I. Zon· 1 shared J. Capella-Pujol· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

J. Schinkel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structure of the hepatitis C virus E1E2 glycoprotein complex

A. Torrents de la Pena, K. Sliepen, L. Eshun-Wilson, M. Newby, J. D. Allen, S. Koekkoek, I. Zon, A. Chumbe, M. Crispin, J. Schinkel, G. C. Lander, R. W. Sanders, A. B. Ward

The paper presents the cryo-EM structure of the HCV E1E2 glycoprotein complex with antibodies, revealing the E1-E2 interface and its stabilization mechanisms.

bioRxiv · Dec 16, 2021 · PreprintImmunology

Optimised cell systems for the investigation ofhepatitis C virus E1E2 glycoproteins

M. D. Kalemera, J. Capella-Pujol, A. Chumbe, A. Underwood, R. A. Bull, J. Schinkel, K. Sliepen, J. Grove

This paper identifies an optimized cell line for producing HCV pseudoparticles and reveals antigenic differences between sE2 produced in 293T and 293F cells.

bioRxiv · Jun 18, 2020 · PreprintMicrobiology

Genotype-matched Newcastle disease virus vaccine confers improved protection against genotype XII challenge: The importance of cytoplasmic tails in viral replication and vaccine design

R. Izquierdo-Lara, A. Chumbe, K. Calderon, M. Fernandez-Diaz, V. N. Vakharia

This study develops a genotype-matched Newcastle disease virus vaccine that improves protection and reduces viral shedding by restoring cytoplasmic tails in vaccine strains.

bioRxiv · Dec 10, 2018Microbiology