Single-component multilayered self-assembling protein nanoparticles presenting glycan-trimmed uncleaved prefusion optimized envelope trimers as HIV-1 vaccine candidates
Y.-N. Zhang, J. Paynter, A. Antanasijevic, J. D. Allen, M. Eldad, Y.-Z. Lee, J. Copps, M. Newby, L. He, D. Chavez, P. Frost, A. E. Goodroe, J. W. Dutton, R. Lanford, C. Chen, , J. Zhu
Glycan trimming of HIV-1 Env immunogens improves vaccine-induced neutralizing antibody responses in small animals and primates.
bioRxiv · Jul 1, 2022Microbiology