Thymic epithelial cell fate and potency in early organogenesis assessed by single cell transcriptional and functional analysis.
A. Chengrui, A. M. Farley, S. Palmer, D. Liu, A. I. Kousa, P. Rouse, V. Major, J. Sweetman, J. Morys, A. Corsinotti, J. Nichols, J. Ure, R. McLay, L. Boulter, J. S. Chapman, , C. C. Blackburn
The paper uses single-cell RNA sequencing to analyze thymic epithelial cell fate and potency in early mouse thymus development, revealing sublineage-primed progenitors and functional bipotency changes.
bioRxiv · Jun 7, 2023 · PreprintDevelopmental Biology