Author

A. I. Kousa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Chengrui· 1 shared A. Corsinotti· 1 shared A. E. Flores· 1 shared A. L. Gomes· 1 shared A. Lazrak· 1 shared A. Lemarquis· 1 shared A. M. Farley· 1 shared B. Gipson· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

A. Chengrui

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2 papers

Recent·Most cited

Thymic epithelial cell fate and potency in early organogenesis assessed by single cell transcriptional and functional analysis.

A. Chengrui, A. M. Farley, S. Palmer, D. Liu, A. I. Kousa, P. Rouse, V. Major, J. Sweetman, J. Morys, A. Corsinotti, J. Nichols, J. Ure, R. McLay, L. Boulter, J. S. Chapman, , C. C. Blackburn

The paper uses single-cell RNA sequencing to analyze thymic epithelial cell fate and potency in early mouse thymus development, revealing sublineage-primed progenitors and functional bipotency changes.

bioRxiv · Jun 7, 2023 · PreprintDevelopmental Biology

Age-related epithelial defects limit thymic function and regeneration

A. I. Kousa, L. Jahn, K. Zhao, A. E. Flores, D. Granadier, K. Cooper, J. M. Sheridan, A. Lemarquis, L. Sikkema, K. V. Argyropoulos, J. Tsai, A. Lazrak, K. Nichols, N. Lee, R. Ghale, , M. R. van den Brink

The paper identifies age-related thymic epithelial cell states that impair thymic regeneration and immune function through spatial and single-cell transcriptomics.

bioRxiv · Dec 16, 2021Immunology