A. D. Lopez-Munoz

Cell Surface Nucleocapsid Protein Expression: A Betacoronavirus Immunomodulatory Strategy

This study shows that N proteins from SARS-CoV-2 and HCoV-OC43 are expressed on cell surfaces, modulating immune responses by binding chemokines and cytokines.

High-throughput engineering of cytoplasmic- and nuclear-replicating large dsDNA viruses by CRISPR/Cas9

This paper optimizes CRISPR/Cas9 for high-throughput generation of marker-free recombinant large dsDNA viruses, improving efficiency and accuracy across cytoplasmic- and nuclear-replicating viruses.

Cell Surface SARS-CoV-2 Nucleocapsid Protein Modulates Innate and Adaptive Immunity

This study shows SARS-CoV-2 nucleocapsid protein binds to chemokines and modulates immune responses, suggesting it as a target for cross-reactive vaccines.

Variations in cell-surface ACE2 levels alter direct binding of SARS-CoV-2 Spike protein and viral infectivity: Implications for measuring Spike protein interactions with animal ACE2 orthologs

This paper develops a cell-based assay to measure SARS-CoV-2 Spike protein binding and infectivity across ACE2 orthologs by normalizing ACE2 expression levels using a reporter protein.

Herpes simpex virus 2 (HSV-2) evolves faster in cell culture than HSV-1 by generating greater genetic diversity

This study shows HSV-2 generates more genetic diversity than HSV-1 in cell culture, leading to higher coding diversity and nonconservative mutations.