Author

A. D. Sahu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:clinical cohort / trial· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

E. Ruppin· 2 shared N. U. Nair· 2 shared A. A. Schaffer· 1 shared A. Amzallag· 1 shared A. Dastur· 1 shared A. Friedman· 1 shared A. S. Halkola· 1 shared A. Tam· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

E. Ruppin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Community Challenge to Predict Clinical Outcomes After Immune Checkpoint Blockade in Non-Small Cell Lung Cancer

M. Mason, O. Lapuente-Santana, A. S. Halkola, W. Wang, R. Mall, X. Xiao, J. Kaufman, J. Fu, J. Pfeil, J. Banerjee, V. Chung, H. Chang, S. D. Chasalow, H. Y. Lin, R. Chai, , B. G. Vincent

The paper evaluates predictive models for immune checkpoint inhibitor outcomes in NSCLC using clinical trial data from two RCTs, finding that models combining PD-L1, TMB, and immune signatures outperform single biomarkers.

Journal of Translational Medicine · Feb 21, 2024Peer-reviewedCancer Biology

Chromosome 7 to the rescue: overcoming chromosome 10 loss in gliomas

N. U. Nair, A. A. Schaffer, M. E. Gertz, K. Cheng, J. Zerbib, A. D. Sahu, G. Leor, E. D. Shulman, K. D. Aldape, U. Ben-David, E. Ruppin

The paper investigates the co-occurrence of chromosome 10 loss and chromosome 7 gain in gliomas, finding functional rescue interactions on chromosome 7 that may compensate for chromosome 10 loss.

bioRxiv · Jan 17, 2024 · PreprintCancer Biology

A landscape of synergistic drug combinations in non-small-cell lung cancer

N. U. Nair, P. Greninger, A. Friedman, A. Amzallag, E. Cortez, A. D. Sahu, J. S. Lee, A. Dastur, R. K. Egan, E. Murchie, G. S. Crowther, J. McClanaghan, J. Boisvert, L. Damon, J. Ho, , C. H. Benes

The paper identifies synergistic drug combinations in non-small-cell lung cancer cell lines, finding that synergy often arises from sensitizing resistant models through dual pathway targeting.

bioRxiv · Jun 3, 2021 · PreprintCancer Biology