Author

K. D. Aldape

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. A. Schaffer· 1 shared A. D. Sahu· 1 shared A. J. Patel· 1 shared C. A. Parada· 1 shared C. Qiu· 1 shared C. W. English· 1 shared D. A. Bonnin· 1 shared D. R. Raleigh· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. A. Schaffer

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2 papers

Recent·Most cited

Meningioma transcriptomic landscape demonstrates novel subtypes with regional associated biology and patient outcome.

H. N. Thirimanne, D. A. Bonnin, N. Nuechterlein, S. Arora, M. Jensen, C. A. Parada, C. Qiu, F. Szulzewsky, C. W. English, W. C. Chen, P. Sievers, F. Nassiri, J. Z. Wang, T. J. Klisch, K. D. Aldape, , E. C. Holland

This study combines bulk RNA-Seq datasets to create a transcriptomic landscape of meningiomas, identifies subtypes with distinct biology and prognosis, and provides an interactive tool for outcome prediction.

bioRxiv · Feb 23, 2024Cancer Biology

Chromosome 7 to the rescue: overcoming chromosome 10 loss in gliomas

N. U. Nair, A. A. Schaffer, M. E. Gertz, K. Cheng, J. Zerbib, A. D. Sahu, G. Leor, E. D. Shulman, K. D. Aldape, U. Ben-David, E. Ruppin

The paper investigates the co-occurrence of chromosome 10 loss and chromosome 7 gain in gliomas, finding functional rescue interactions on chromosome 7 that may compensate for chromosome 10 loss.

bioRxiv · Jan 17, 2024 · PreprintCancer Biology