BioengineeringbioRxiv
In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles
F.-Y. Su, Q. Zhao, S. N. Dahotre…·G. A. Kwong
The paper develops a method to deliver mRNA to multiple virus-specific T cells using light-induced ligand exchange of MHC class I antigen-presenting nanoparticles, achieving ~50% transfection in vivo.