Author

P. Santangelo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

A. D. Silva Trenkle· 1 shared A. Gaisin· 1 shared A. Zamat· 1 shared B. Owen· 1 shared C. Carter· 1 shared C. Cicala· 1 shared C. T. Thuruthiyil· 1 shared D. Bose· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioengineering

A. D. Silva Trenkle

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Blockade of TGF-β signaling reactivates HIV-1/SIV reservoirs and immune responses in vivo

S. Samer, Y. Thomas, M. Arainga, C. Carter, L. M. Shirreff, M. S. Arif, J. M. Avitia, I. Frank, M. D. McRaven, C. T. Thuruthiyil, V. B. Heybeli, M. R. Anderson, B. Owen, A. Gaisin, D. Bose, , E. Marinelli

This study shows that blocking TGF-β signaling increases HIV-1 and SIV reactivation and boosts immune responses in infected individuals on ART.

bioRxiv · May 13, 2022Immunology

In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles

F.-Y. Su, Q. Zhao, S. N. Dahotre, L. Gamboa, S. S. Bawage, A. D. Silva Trenkle, A. Zamat, H. Phuengkham, R. Ahmed, P. Santangelo, G. A. Kwong

The paper develops a method to deliver mRNA to multiple virus-specific T cells using light-induced ligand exchange of MHC class I antigen-presenting nanoparticles, achieving ~50% transfection in vivo.

bioRxiv · Oct 14, 2021Bioengineering