Author

A. Deutsch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 3 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

S. Syga· 2 shared A. Voss-Böhme· 1 shared B. Bekker· 1 shared B. Klink· 1 shared H. Hatzikirou· 1 shared H. P. Jain· 1 shared K. Wolf· 1 shared L. Beunk· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

S. Syga

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Evolution of phenotypic plasticity leads to tumor heterogeneity with implications for therapy

S. Syga, H. P. Jain, M. Krellner, H. Hatzikirou, A. Deutsch

This paper investigates how somatic evolution and phenotypic plasticity interact in glioblastoma, showing that phenotypic heterogeneity, not genetic diversity, better predicts poor treatment outcomes.

PLOS Computational Biology · Aug 9, 2024Peer-reviewedCancer Biology

Extracellular matrix guidance determines proteolytic and non-proteolytic cancer cell patterning

L. Beunk, S. van Helvert, B. Bekker, L. Ran, R. Kang, T. Paulat, S. Syga, A. Deutsch, P. Friedl, K. Wolf

This study shows that matrix density and guidance cues determine whether cancer cells use proteolytic or non-proteolytic invasion strategies in 3D tissue.

bioRxiv · Mar 16, 2022 · PreprintCancer Biology

Patterns of tumor progression predict small and tissue-specific tumor-originating niches

T. Buder, A. Deutsch, B. Klink, A. Voss-Böhme

The paper estimates the minimal number of tumor cells required for tumor formation in human tissues and proposes the existence of small, tissue-specific tumor-originating niches.

bioRxiv · May 25, 2018Cancer Biology