R. Kang

LGR4 is essential for maintaining beta-cell homeostasis through suppression of RANK

This study shows LGR4 maintains beta-cell health by suppressing RANK, with effects observed in both in vitro and mouse models under stress and aging.

Single Cell RNA-Seq Analysis of Regenerative Drug-Treated Human Pancreatic Islets Identifies A Cycling Alpha Cell Population As Key Beta Cell Progenitors

This study uses single-cell RNA sequencing to identify cycling alpha cells as key beta cell progenitors in response to DYRK1A inhibitor treatment in human pancreatic islets.

Sequence-based prediction of the solubility of peptides containing non-natural amino acids

The paper presents CamSol-PTM, a computational method to predict solubility of peptides with non-natural amino acids, validated through experimental testing of 30 variants.

High-quality nuclear genome and mitogenome of Bipolaris sorokiniana strain LK93, a devastating pathogen causing wheat root rot

The paper sequences and assembles the nuclear and mitochondrial genomes of Bipolaris sorokiniana strain LK93 to improve understanding of its interaction with wheat.

Sequence-based pH-dependent prediction of protein solubility using CamSol

The paper extends the CamSol method to predict protein solubility at different pH levels and validates it on antibodies and other proteins.

Extracellular matrix guidance determines proteolytic and non-proteolytic cancer cell patterning

This study shows that matrix density and guidance cues determine whether cancer cells use proteolytic or non-proteolytic invasion strategies in 3D tissue.