Author

A. F. O'Donnell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:yeast· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

E. M. Jordahl· 2 shared R. W. Bowman· 2 shared A. Chiang· 1 shared A. McLysaght· 1 shared A. Nikiforov· 1 shared A. Wacholder· 1 shared A.-R. Carvunis· 1 shared B. Hsu· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

E. M. Jordahl

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Author profile →

3 papers

Recent·Most cited

Hexokinase 2 localizes to the nucleus in response to glucose limitation but does not regulate gene expression

M. A. Lesko, D. G. Chandrashekarappa, E. M. Jordahl, K. G. Oppenheimer, R. W. Bowman, C. Shang, J. Durrant, M. C. Schmidt, A. F. O'Donnell

This study uses live-cell imaging to show that Hxk2 localizes to the nucleus under glucose limitation, contradicting previous findings, and finds it does not regulate gene expression.

bioRxiv · Nov 30, 2022 · PreprintCell Biology

Alpha-arrestins Aly1 and Aly2 regulate trafficking of the glycerophosphoinositol transporter Git1 and impact phospholipid homeostasis

B. P. Robinson, S. E. Hawbaker, A. Chiang, E. M. Jordahl, S. Anaokar, A. Nikiforov, R. W. Bowman, P. Ziegler, C. K. McAtee, J. Patton-Vogt, A. F. O'Donnell

This paper shows that alpha-arrestins Aly1 and Aly2 regulate Git1 trafficking and phospholipid homeostasis in yeast by controlling Git1 localization and GPI metabolism.

bioRxiv · Feb 4, 2021Cell Biology

De novo emergence of adaptive membrane proteins from thymine-rich intergenic sequences

N. Vakirlis, O. Acar, B. Hsu, N. Castilho Coelho, S. B. Van Oss, A. Wacholder, K. Medetgul-Ernar, J. Ianotta, A. McLysaght, C. J. Camacho, A. F. O'Donnell, T. Ideker, A.-R. Carvunis

This study shows that de novo emerging coding sequences in yeast often encode beneficial transmembrane proteins, suggesting that intergenic regions may contain pre-existing blueprints for such functions.

bioRxiv · Apr 29, 2019Evolutionary Biology