Author

A. Fago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Evolutionary Biology· 3 Physiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

C. Natarajan· 4 shared J. F. Storz· 3 shared A. V. Signore· 2 shared N. M. Bautista· 2 shared B. Venkatesh· 1 shared C. J. Brauner· 1 shared C. M. Ivy· 1 shared E. E. Petersen· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersEvolutionary Biology

C. Natarajan

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Evolution of an extreme hemoglobin phenotype contributed to the sub-Arctic specialization of extinct Steller's sea cows

A. V. Signore, P. R. Morrison, C. J. Brauner, A. Fago, R. E. Weber, K. L. Campbell

This paper identifies an amino acid substitution in Steller's sea cow hemoglobin that altered oxygen affinity and solubility, contributing to their cold adaptation.

bioRxiv · Aug 29, 2022Evolutionary Biology

Evolution and molecular basis of a novel allosteric property of crocodilian hemoglobin

C. Natarajan, A. V. Signore, N. M. Bautista, F. G. Hoffmann, J. R. Tame, A. Fago, J. F. Storz

This study investigates the molecular basis of a novel allosteric property in crocodilian hemoglobin by resurrecting ancestral proteins and performing directed mutagenesis.

bioRxiv · Jul 18, 2022Evolutionary Biology

New insights into the allosteric effects of CO2 and bicarbonate on crocodilian hemoglobin

N. M. Bautista, H. Malte, C. Natarajan, T. Wang, J. F. Storz, A. Fago

This study provides the first experimental evidence that bicarbonate binds directly to crocodilian hemoglobin, promoting O2 delivery independently of CO2.

Journal of Experimental Biology · Aug 2, 2021Peer-reviewedPhysiology

Genetic variation in haemoglobin regulates breathing in high-altitude deer mice

C. M. Ivy, O. Wearing, C. Natarajan, R. M. Schweizer, N. Gutierrez-Pinto, J. P. Velotta, S. C. Campbell-Staton, E. E. Petersen, A. Fago, Z. A. Cheviron, J. F. Storz, G. R. Scott

This study shows that genetic variation in haemoglobin affects breathing patterns in high-altitude deer mice, independent of its role in oxygen transport.

bioRxiv · Feb 23, 2021 · PreprintEvolutionary Biology

Oxygenation properties of hemoglobin and the evolutionary origins of isoform multiplicity in an amphibious air-breathing fish, the blue-spotted mudskipper (Boleophthalmus pectinirostris)

J. Storz, C. Natarajan, M. Grouleff, M. Vandewege, F. Hoffmann, X. You, B. Venkatesh, A. Fago

This study examines hemoglobin oxygenation properties and genomic origins of isoform multiplicity in the blue-spotted mudskipper, finding similar oxygen transport traits to hypoxia-tolerant fish despite functional isoform diversity.

bioRxiv · Oct 25, 2019Physiology