Author

X. You

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Animal Behavior & Cognition· 1 Cancer Biology· 1 Microbiology· 1 Physiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cancer & tumor microenvironment· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

L. Zhang· 2 shared S. Sun· 2 shared S.-F. Sui· 2 shared A. A. Mangaonkar· 1 shared A. Buradkar· 1 shared A. Chatzinotas· 1 shared A. Fago· 1 shared A. Vedder· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersPlant Biology

L. Zhang

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Author profile →

7 papers

Recent·Most cited

In situ structural determination of cyanobacterial phycobilisome-PSII supercomplex by STAgSPA strategy

X. Zhang, Y. Xiao, X. You, S. Sun, S.-F. Sui

The paper develops a method called STAgSPA to determine the in situ structure of a cyanobacterial PBS-PSII supercomplex at 3.5 Å resolution, revealing energy transfer mechanisms and structural coupling.

bioRxiv · Dec 17, 2023 · PreprintBiophysics

Probucol mitigates high-fat diet-induced cognitive and social impairments through disruption of redox-inflammation association

H.-M. Wu, N.-J. Huang, Y. V. Yang, L.-P. Fan, T.-Y. Tang, L. Liu, Y. Xu, D.-T. Liu, Z.-X. Cai, X.-Y. Ren, Z.-H. Yao, J.-Z. Chen, X. Huang, C. Zhang, X. You, , S.-Y. Lin

This study shows probucol reduces high-fat diet-induced cognitive and social impairments in mice without affecting obesity or metabolic homeostasis, by disrupting redox-inflammation links.

bioRxiv · Sep 5, 2023Animal Behavior & Cognition

Cytomixis and aberrant phenomena during meiosis in pollen mother cells of Camellia sinensis var. sinensis cv 'Fudingdabai'

X. Yu, X. You, L. Zhang, X. Li

The study examines meiotic behavior in tea plant pollen mother cells, identifying normal and abnormal phenomena including cytomixis and other meiotic errors.

bioRxiv · Apr 15, 2023 · PreprintPlant Biology

Structural basis for assembly of TRAPPII complex and specific activation of GTPase Ypt31/32

C. Mi, L. Zhang, S. Sun, G. Huang, G. Shao, F. Yang, X. You, M.-Q. Dong, S.-F. Sui

The paper presents cryo-EM structures of yeast TRAPPII complex in apo and Ypt32-bound states, revealing its assembly mechanism and specific activation of Ypt31/Ypt32.

bioRxiv · Nov 11, 2021Biophysics

Phage co-transport with hyphal-riding bacteria fuels bacterial invasion in water-unsaturated microbial ecosystems

X. You, R. Kallies, I. Kühn, M. Schmidt, H. Harms, A. Chatzinotas, L. Y. Wick

The paper shows hyphal-riding bacteria transport phages to new habitats, enhancing their colonization success in water-unsaturated environments.

bioRxiv · Jul 28, 2021Microbiology

RAS mutations drive proliferative chronic myelomonocytic leukemia via activation of a novel KMT2A-PLK1 axis

R. M. Carr, D. Vorobyev, T. Lasho, D. L. Marks, E. J. Tolosa, A. Vedder, L. Almada, A. Yurchenko, I. Padioleau, B. Alver, G. Coltro, M. Binder, S. L. Safgren, I. Horn, X. You, , M. M. Patnaik

This study identifies RAS mutations as drivers of proliferative CMML through a novel KMT2A-PLK1 axis, showing PLK1 inhibition can improve disease outcomes in patient-derived xenografts.

bioRxiv · Dec 23, 2019 · PreprintCancer Biology

Oxygenation properties of hemoglobin and the evolutionary origins of isoform multiplicity in an amphibious air-breathing fish, the blue-spotted mudskipper (Boleophthalmus pectinirostris)

J. Storz, C. Natarajan, M. Grouleff, M. Vandewege, F. Hoffmann, X. You, B. Venkatesh, A. Fago

This study examines hemoglobin oxygenation properties and genomic origins of isoform multiplicity in the blue-spotted mudskipper, finding similar oxygen transport traits to hypoxia-tolerant fish despite functional isoform diversity.

bioRxiv · Oct 25, 2019Physiology