Author

F. G. Hoffmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 9

Signature Assays, Organisms & Methods

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Approach:statistical model· 6 Organism:multiple species· 5 Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:phylogenetics / evolution· 2 Assay:proteomics· 2

Frequent Co-Authors

J. C. Opazo· 3 shared K. Zavala· 3 shared A. V. Signore· 2 shared J. F. Storz· 2 shared A. C. Black· 1 shared A. Costabile· 1 shared A. Fago· 1 shared A. I. Furness· 1 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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3 shared papersEvolutionary Biology

J. C. Opazo

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9 papers

Recent·Most cited

Horizontally transferred glycoside hydrolase 26 may aid hemipteran insects in plant tissue digestion

H. K. Walt, S.-J. Ahn, F. G. Hoffmann

This study identifies a horizontally transferred glycoside hydrolase 26 gene from bacteria to Hemiptera insects, showing its adaptive role in plant tissue digestion through high expression in salivary glands.

bioRxiv · Apr 15, 2024Evolutionary Biology

Evolutionary analysis of genome-specific duplications in flatworm genomes

M. Langleib, J. Calvelo, A. Costabile, E. Castillo, J. F. Tort, F. G. Hoffmann, A. V. Protasio, U. Koziol, A. Iriarte

This study analyzes genome-specific duplications in flatworms, finding overrepresented functional categories and conserved expression patterns among inparalogs, supporting gene duplication's role in their evolution.

bioRxiv · Feb 5, 2024 · PreprintEvolutionary Biology

Evolution and molecular basis of a novel allosteric property of crocodilian hemoglobin

C. Natarajan, A. V. Signore, N. M. Bautista, F. G. Hoffmann, J. R. Tame, A. Fago, J. F. Storz

This study investigates the molecular basis of a novel allosteric property in crocodilian hemoglobin by resurrecting ancestral proteins and performing directed mutagenesis.

bioRxiv · Jul 18, 2022Evolutionary Biology

Deterministic shifts in molecular evolution correlate with convergence to annualism in killifishes

A. W. Thompson, A. C. Black, Y. Huang, Q. Shi, A. I. Furness, I. Braasch, F. G. Hoffmann, G. Orti

The paper shows that annual life history in killifishes is linked to higher evolutionary rates in genes involved in development and metabolism.

bioRxiv · Aug 9, 2021 · PreprintEvolutionary Biology

The PIWI/piRNA response is relaxed in a rodent that lacks mobilizing transposable elements

M. W. Vandewege, R. N. Platt, D. K. Merriman, D. A. Ray, F. G. Hoffmann

The study examines PIWI/piRNA dynamics in 13-lined ground squirrels lacking mobilizing transposable elements, finding reduced PIWI expression and minimal TE transcriptional suppression.

bioRxiv · Jun 14, 2021Evolutionary Biology

Evolved increases in hemoglobin-oxygen affinity and Bohr effect coincided with the aquatic specialization of penguins.

A. V. Signore, M. S. Tift, F. G. Hoffmann, T. L. Schmitt, H. Moriyama, J. F. Storz

This study investigates how penguins evolved increased hemoglobin-oxygen affinity and Bohr effect to enhance diving capabilities by optimizing oxygen extraction and release during breath-hold dives.

bioRxiv · Nov 17, 2020Evolutionary Biology

How many sirtuin genes are out there? evolution of sirtuin genes in vertebrates with a description of a new family member

J. C. Opazo, M. Vandewege, F. G. Hoffmann, K. Zavala, C. Melendez, C. Luchsinger, V. Cavieres, L. Vargas-Chacoff, F. Morera, P. Burgos, C. Tapia-Rojas, G. Mardones

The paper investigates the evolutionary history of sirtuin genes in vertebrates, identifying a new family member and showing at least eight paralogs traceable to a common ancestor.

bioRxiv · Jul 17, 2020Evolutionary Biology

Evolution of the DAN gene family in vertebrates

J. C. Opazo, F. G. Hoffmann, K. Zavala, S. V. Edwards

This study investigates the evolutionary history of the DAN gene family in vertebrates, revealing its monophyly and identifying new gene lineages and differential loss patterns across species.

bioRxiv · Jun 29, 2020Evolutionary Biology

Evolution of Nodal and Nodal-related genes and the putative composition of the heterodimer that triggers the Nodal pathway in vertebrates

J. C. Opazo, S. Kuraku, K. Zavala, J. Toloza-Villalobos, F. G. Hoffmann

This study investigates the evolutionary history of Nodal and Nodal-related genes in vertebrates and infers the composition of Nodal pathway-activating heterodimers.

bioRxiv · Nov 30, 2018Evolutionary Biology