Author

A. G. Kozlov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Organism:E. coli· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Assay:protein structure· 1

Frequent Co-Authors

T. M. Lohman· 4 shared B. Nguyen· 2 shared A. Chadda· 1 shared E. Galburt· 1 shared E. Weiland· 1 shared E. Zytkiewicz· 1 shared H. Zhang· 1 shared I. A. Shkel· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersBiophysics

T. M. Lohman

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Author profile →

4 papers

Recent·Most cited

Mycobacterium tuberculosis Ku stimulates multi-round DNA unwinding by UvrD1 monomers

A. Chadda, A. G. Kozlov, B. Nguyen, T. M. Lohman, E. Galburt

This study shows that Mtb Ku stimulates UvrD1 monomers to unwind DNA in multiple rounds, revealing a mechanism for DNA repair activation in mycobacteria.

bioRxiv · Sep 29, 2023 · PreprintBiophysics

How Glutamate Promotes Liquid-liquid Phase Separation and DNA Binding Cooperativity of E. coli SSB Protein

A. G. Kozlov, X. Cheng, H. Zhang, M. K. Shinn, E. Weiland, B. Nguyen, I. A. Shkel, E. Zytkiewicz, I. J. Finkelstein, M. T. Record, T. M. Lohman

This study shows that potassium glutamate promotes liquid-liquid phase separation and non-nearest-neighbor cooperativity of E. coli SSB protein through amide group interactions, while KCl inhibits these processes.

bioRxiv · Jan 17, 2022Biochemistry

Probing E. coli SSB Protein-DNA topology by reversing DNA backbone polarity

T. M. Lohman, A. G. Kozlov

This study investigates how E. coli and P. falciparum SSB proteins bind ssDNA with reversed backbone polarity, finding that both maintain strict polarity preference but adapt their wrapping topology.

bioRxiv · Dec 5, 2020Biophysics

Comparative analysis of CPI-motif regulation of biochemical functions of actin capping protein

P. McConnell, M. Mekel, A. G. Kozlov, O. L. Mooren, T. M. Lohman, J. A. Cooper

The paper compares the biochemical functions of CPI-motif-containing peptides from different protein families and identifies sequence variations affecting their interactions with actin capping protein.

bioRxiv · Feb 6, 2020Biochemistry