Author

P. McConnell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

J. A. Cooper· 3 shared O. L. Mooren· 3 shared A. G. Kozlov· 1 shared A. Jaysingh· 1 shared A. Soranno· 1 shared C. Yan· 1 shared D. Goldfarb· 1 shared D. Sept· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

J. A. Cooper

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Reconstitution of Arp2/3-Nucleated Actin Assembly with CP, V-1 and CARMIL

O. L. Mooren, P. McConnell, J. D. DeBrecht, A. Jaysingh, J. A. Cooper

The paper investigates whether CPI-motif proteins activate or inhibit Arp2/3-mediated actin assembly by reconstituting the system with purified components and finds that CARMIL promotes actin assembly by counteracting V-1 inhibition.

bioRxiv · May 13, 2024Cell Biology

Biophysical Mechanism of Allosteric Regulation of Actin Capping Protein

O. L. Mooren, M. D. Stuchell-Brereton, P. McConnell, C. Yan, E. M. Wilkerson, D. Goldfarb, J. A. Cooper, D. Sept, A. Soranno

This study investigates the biophysical mechanism of allosteric regulation of actin capping protein using single-molecule FRET and MD simulations, revealing conformational changes linked to ligand binding.

bioRxiv · Aug 16, 2023Biochemistry

Comparative analysis of CPI-motif regulation of biochemical functions of actin capping protein

P. McConnell, M. Mekel, A. G. Kozlov, O. L. Mooren, T. M. Lohman, J. A. Cooper

The paper compares the biochemical functions of CPI-motif-containing peptides from different protein families and identifies sequence variations affecting their interactions with actin capping protein.

bioRxiv · Feb 6, 2020Biochemistry