Author

A. Gaggar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

X. Xu· 2 shared A. J. Gehring· 1 shared A. Mehrotra· 1 shared A. Patel· 1 shared B. C. Hunt· 1 shared C. Margaroli· 1 shared C. Song· 1 shared C. V. Lal· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersMicrobiology

X. Xu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Virus-associated Inflammation Imprints an Inflammatory Profile on Long-lived Monocyte-derived Macrophages in the Human Liver

J.-D. Sanchez, S. Nkongolo, D. Traum, S. C. Kim, D. Mahamed, A. Mehrotra, A. Patel, D. Chen, S. Fung, A. Gaggar, J. J. Feld, K.-M. Chang, J. J. Wallin, H. L. A. Janssen, A. J. Gehring

The paper shows that chronic inflammation in the liver leads to the formation of long-lived inflammatory macrophages derived from monocytes, which retain an inflammatory profile and may drive liver disease progression.

bioRxiv · Jan 31, 2024 · PreprintImmunology

Neutrophilic Inflammation in Models of Bronchopulmonary Dysplasia and Chronic Obstructive Pulmonary Disease is Rescued by a Lactobacilli Based Live Biotherapeutic

T. Nicola, N. Wenger, X. Xu, M. Evans, G. Rezonzew, L. Qiao, Y. Yang, N. Ambalavanan, J. E. Blalock, A. Gaggar, C. V. Lal

This study shows that a lactobacilli-based live biotherapeutic reduces neutrophilic inflammation and improves lung function in models of BPD and COPD.

bioRxiv · Mar 2, 2023 · PreprintMicrobiology

Spatial transcriptomic profiling of coronary endothelial cells in SARS-CoV-2 myocarditis

C. Margaroli, P. Benson, M. G. Gastanadui, C. Song, L. Viera, D. Xing, J. M. Wells, R. Patel, A. Gaggar, G. A. Payne

This study uses spatial transcriptomics to analyze SARS-CoV-2 infection in coronary endothelial and myocardial tissues from COVID-19 patients, finding unique pro-inflammatory profiles in capillaries but not larger vessels.

bioRxiv · Sep 25, 2022Pathology

Nontypeable Haemophilus influenzae redox recycling of protein thiols promotes resistance to oxidative killing and bacterial survival in biofilms in a smoke related infection model

B. C. Hunt, X. Xu, A. Gaggar, W. E. Swords

This study shows that thiol redox homeostasis in NTHi promotes biofilm persistence and oxidative resistance in a smoke-related infection model.

bioRxiv · Aug 25, 2021Microbiology