S. C. Kim

Spatial polarization of endothelial ICAM-1 governs T-cell exclusion in melanoma

This study identifies endothelial ICAM-1 as a regulator of T-cell exclusion in melanoma by spatially polarizing its expression, and shows that blocking ICAM-1 enhances T-cell infiltration and immunotherapy efficacy.

Diaminopurine in Nonenzymatic RNA Template Copying

This study investigates whether replacing adenine with diaminopurine in nonenzymatic RNA template copying improves efficiency and reduces bias.

Virus-associated Inflammation Imprints an Inflammatory Profile on Long-lived Monocyte-derived Macrophages in the Human Liver

The paper shows that chronic inflammation in the liver leads to the formation of long-lived inflammatory macrophages derived from monocytes, which retain an inflammatory profile and may drive liver disease progression.

CD28-Selective Inhibition Prolongs Non-Human Primate Kidney Transplant Survival

This study tests a CD28-selective therapy in non-human primates, showing extended kidney transplant survival compared to belatacept alone.

Spatial and compositional variations in fruit characteristics of papaya (Carica papaya cv. Tainung No. 2) during ripening

This study examines spatial and compositional changes in papaya fruit characteristics during ripening across different fruit parts and stages.

Enhanced production of natural shiga toxin by overexpressing A subunit of Stx2e in Stx2e-producing Escherichia coli isolated in South Korea

This study enhances Stx2e production in STEC 150229 by overexpressing the A subunit, resulting in higher cytotoxicity against Vero cells.

Non-enzymatic primer extension with strand displacement

This study demonstrates non-enzymatic RNA primer extension through strand displacement using short RNA oligonucleotides, suggesting a prebiotic mechanism for RNA replication.

Particle-templated emulsification for microfluidics-free digital biology

This paper introduces a method to create monodispersed emulsions for biological applications without using microfluidics, demonstrating its use in ddPCR and single cell culture.

Robotic automation of droplet microfluidics

This paper demonstrates robotically-automated droplet microfluidics to streamline complex workflows, enhancing reliability and convenience through commercial fluid-handling robots.