Author

A. Gazzo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

B. Weigelt· 2 shared Y. Zhu· 2 shared A. A. Jungbluth· 1 shared A. Gupta· 1 shared A. L. F. Longhini· 1 shared A. Marra· 1 shared A. Safonov· 1 shared B. D. Greenbaum· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

B. Weigelt

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2 papers

Recent·Most cited

APOBEC3 mutagenesis drives therapy resistance in breast cancer

A. Gupta, A. Gazzo, P. Selenica, A. Safonov, F. Pareja, E. M. da Silva, D. N. Brown, Y. Zhu, J. Patel, J. Blanco-Heredia, B. Stefanovska, M. A. Carpenter, X. Pei, D. Frosina, A. A. Jungbluth, , S. Chandarlapaty

This study identifies APOBEC3 mutagenesis as a common driver of therapy resistance in breast cancer, associated with poorer clinical outcomes.

bioRxiv · Apr 29, 2024Cancer Biology

Interferon response and epigenetic modulation by SMARCA4 mutations drive ovarian tumor immunogenicity

M. N. Brodeur, H. Dopeso, Y. Zhu, A. L. F. Longhini, A. Gazzo, S. Sun, R. Koche, R. Qu, P.-J. Hamard, Y. Bykov, H. Green, K. B. Chiappinelli, M. A. Ozsoy, T. Basili, R. Gardner, , D. Zamarin

This study shows that SMARCA4 mutations in ovarian cancer increase immunogenicity through interferon response and epigenetic changes, enhancing T cell and NK cell activity in the tumor microenvironment.

bioRxiv · Aug 8, 2023 · PreprintCancer Biology