Author

A. Goemer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. Todt· 3 shared R. J. P. Brown· 3 shared B. Qu· 2 shared C. Miskey· 2 shared A. Balkema-Buschmann· 1 shared A. Breithaupt· 1 shared A. Ebenig· 1 shared A. W. Tarr· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

D. Todt

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Targeting cellular cathepsins inhibits hepatitis E virus infection

M. Kloehn, T. Burkard, J. Janzen, J. A. Schrader, A. Goemer, R. J. P. Brown, V. L. Dao Thi, V. Kinast, Y. Brueggemann, D. Todt, E. Steinmann

This study identifies lysosomal cathepsins, particularly CTSL, as critical for HEV entry and demonstrates the antiviral efficacy of the pan-cathepsin inhibitor K11777.

bioRxiv · Nov 3, 2023 · PreprintCell Biology

Spatiotemporal analysis of SARS-CoV-2 infection reveals an expansive wave of monocyte-derived macrophages associated with vascular damage and virus clearance in hamster lungs

O. Bagato, A. Balkema-Buschmann, D. Todt, S. Weber, A. Goemer, B. Qu, C. Miskey, T. C. Mettenleiter, S. Finke, R. J. P. Brown, A. Breithaupt, D. S. Ushakov

This study uses 3D spatiotemporal analysis to show that SARS-CoV-2 infection in hamsters leads to monocyte-derived macrophage infiltration, vascular damage, and virus clearance, followed by tissue remodeling and fibrosis.

bioRxiv · Mar 22, 2023Immunology

SARS-CoV-2 entry route impacts a range of downstream viral and cellular processes

B. Qu, C. Miskey, A. Goemer, D. Potmus, M. Nocke, R. D. V. Kleinert, T. K. Itotia, L. Valder, J. Brueckmann, S. Hoeck, F. D. Hastert, C. von Rhein, C. Schuermann, A. Ebenig, M. Widera, , R. J. P. Brown

This study shows that SARS-CoV-2 entry via TMPRSS2 or endolysosomal cathepsins affects viral replication, immune response, and genome evolution.

bioRxiv · Aug 5, 2022 · PreprintMicrobiology