Author

M. Kloehn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

D. Todt· 2 shared E. Steinmann· 2 shared V. L. Dao Thi· 2 shared A. Goemer· 1 shared J. A. Schrader· 1 shared J. A. Wheis· 1 shared J. Hu· 1 shared J. Janzen· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

D. Todt

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Targeting cellular cathepsins inhibits hepatitis E virus infection

M. Kloehn, T. Burkard, J. Janzen, J. A. Schrader, A. Goemer, R. J. P. Brown, V. L. Dao Thi, V. Kinast, Y. Brueggemann, D. Todt, E. Steinmann

This study identifies lysosomal cathepsins, particularly CTSL, as critical for HEV entry and demonstrates the antiviral efficacy of the pan-cathepsin inhibitor K11777.

bioRxiv · Nov 3, 2023 · PreprintCell Biology

A high-content RNA-based imaging assay reveals integrin beta 1 as a cofactor for cell entry of non-enveloped hepatitis E virus

R. M. Fu, Z. Engels, J. A. Wheis, J. Muerle, M. Kloehn, D. Todt, J. Hu, E. Steinmann, T. Boettler, P.-Y. Lozach, S. M. Lemon, V. L. Dao Thi

This study identifies integrin beta 1 as a cofactor for naked hepatitis E virus entry, revealing distinct endocytic pathways for naked and enveloped HEV particles.

bioRxiv · Oct 27, 2023 · PreprintMicrobiology