Author

A. Balkema-Buschmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 4 Organism:rat· 3 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

A. Breithaupt· 3 shared T. C. Mettenleiter· 3 shared A. Aebischer· 2 shared A. Dorhoi· 2 shared C. Blaurock· 2 shared C. Wylezich· 2 shared D. Hoeper· 2 shared D. Hoffmann· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

A. Breithaupt

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Reconstructing bat antiviral immunity using epithelial organoids

M. J. Kellner, P. Zelger, V. Monteil, G. Pei, M. Onji, K. Nayak, M. Zilbauer, A. Balkema-Buschmann, A. Dorhoi, A. Mirazimi, J. M. Penninger

This study uses bat epithelial organoids to investigate antiviral immunity differences between bats and humans, revealing unique interferon responses and implications for viral pathogenesis.

bioRxiv · Apr 5, 2024 · PreprintImmunology

Cytoarchitecture of SARS-CoV-2 infected hamster lungs by X-ray phase contrast tomography: imaging workflow and classification for drug testing

J. Reichmann, C. Sarrazin, S. Schmale, C. Blaurock, A. Balkema-Buschmann, B. Schmitzer, T. Salditt

The paper develops a workflow for high-throughput X-ray phase contrast tomography to quantify and classify lung cytoarchitecture in SARS-CoV-2 infected hamsters, enabling drug effect analysis.

bioRxiv · Jan 21, 2024 · PreprintPathology

Spatiotemporal analysis of SARS-CoV-2 infection reveals an expansive wave of monocyte-derived macrophages associated with vascular damage and virus clearance in hamster lungs

O. Bagato, A. Balkema-Buschmann, D. Todt, S. Weber, A. Goemer, B. Qu, C. Miskey, T. C. Mettenleiter, S. Finke, R. J. P. Brown, A. Breithaupt, D. S. Ushakov

This study uses 3D spatiotemporal analysis to show that SARS-CoV-2 infection in hamsters leads to monocyte-derived macrophage infiltration, vascular damage, and virus clearance, followed by tissue remodeling and fibrosis.

bioRxiv · Mar 22, 2023Immunology

Compellingly high SARS-CoV-2 susceptibility of Golden Syrian hamsters suggests multiple zoonotic infections of pet hamsters during the COVID-19 pandemic

C. Blaurock, A. Breithaupt, S. Weber, C. Wylezich, M. Keller, B.-P. Mohl, D. Goerlich, M. H. Groschup, B. Sadeghi, D. Hoeper, T. C. Mettenleiter, A. Balkema-Buschmann

This study determines the minimum infective dose of SARS-CoV-2 for Golden Syrian hamsters and highlights their high susceptibility, suggesting a potential zoonotic risk.

bioRxiv · Apr 19, 2022Microbiology

Multi-species ELISA for the detection of antibodies against SARS-CoV-2 in animals

K. Wernike, A. Aebischer, A. Michelitsch, D. Hoffmann, C. Freuling, A. Balkema-Buschmann, A. Graaf, T. Mueller, N. Osterrieder, M. Rissmann, D. Rubbenstroth, J. Schoen, C. Schulz, J. Trimpert, L. Ulrich, , M. Beer

The paper develops a multi-species ELISA to detect SARS-CoV-2 antibodies in animals, achieving 100% specificity and 98.31% sensitivity across multiple species.

bioRxiv · Aug 26, 2020Microbiology

Susceptibility of raccoon dogs for experimental SARS-CoV-2 infection

C. M. Freuling, A. Breithaupt, T. Mueller, J. Sehl, A. Balkema-Buschmann, M. Rissmann, A. Klein, C. Wylezich, D. Hoeper, K. Wernike, A. Aebischer, D. Hoffmann, V. Friedrichs, A. Dorhoi, M. Groschup, , T. C. Mettenleiter

This study shows raccoon dogs are susceptible to SARS-CoV-2 infection and can transmit it to direct contact animals, suggesting they may act as intermediate hosts.

bioRxiv · Aug 19, 2020Microbiology